Tenofovir (R)-Propanol Impurity
R-(+)-9-(2-Hydroxypropyl)adenine
CAS: 14047-28-0
Molecular Formula: C8H11N5O
Tenofovir (R)-Propanol Impurity - Names and Identifiers
Tenofovir (R)-Propanol Impurity - Physico-chemical Properties
| Molecular Formula | C8H11N5O |
| Molar Mass | 193.21 |
| Density | 1.57 |
| Melting Point | 193 °C |
| Boling Point | 457.7±55.0 °C(Predicted) |
| Flash Point | 230.6°C |
| Solubility | DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly, Heated) |
| Vapor Presure | 3.6E-09mmHg at 25°C |
| Appearance | Solid |
| Color | White to Off-White |
| pKa | 14.42±0.20(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
| Refractive Index | 1.752 |
| Physical and Chemical Properties | White powder solid |
Tenofovir (R)-Propanol Impurity - Introduction
(R)-9-(2-Hydroxypropyl) adenine, also known as (R)-ABCG, is a chemical substance with the following chemical structure:
Nature:
(R)-9-(2-Hydroxypropyl) adenine is a white solid that is stable at room temperature. It is sparingly soluble in water and soluble in organic solvents such as methanol and methylene chloride. It has high thermal and chemical stability.
Use:
(R)-9-(2-hydroxypropyl) adenine is mainly used in the field of medicine, as a potential drug molecule or drug intermediate. It has broad-spectrum antiviral, anticancer and immunomodulatory activities. It may be used in the development of anti-HIV drugs or as an integral part of antiviral drug formulations.
Preparation Method:
The preparation method of (R)-9-(2-hydroxypropyl) adenine is more complicated, and it is usually synthesized by organic synthesis reaction. Specific methods may vary according to different research needs.
Safety Information:
(R)-9-(2-Hydroxypropyl) adenine is a relatively safe chemical under normal operating conditions. However, because it is a chemical substance, it is still necessary to follow safe operating procedures when using and storing it. When exposed to (R)-9-(2-hydroxypropyl) adenine, care should be taken to avoid contact with eyes, skin, and respiratory tract, and protective gloves and goggles should be worn. At the same time, the safety operation regulations in the laboratory should be followed, and the safety data form or safety manual of the product should be read carefully before use. If you accidentally come into contact with (R)-9-(2-hydroxypropyl) adenine, rinse immediately with plenty of water and seek medical help if needed.
Nature:
(R)-9-(2-Hydroxypropyl) adenine is a white solid that is stable at room temperature. It is sparingly soluble in water and soluble in organic solvents such as methanol and methylene chloride. It has high thermal and chemical stability.
Use:
(R)-9-(2-hydroxypropyl) adenine is mainly used in the field of medicine, as a potential drug molecule or drug intermediate. It has broad-spectrum antiviral, anticancer and immunomodulatory activities. It may be used in the development of anti-HIV drugs or as an integral part of antiviral drug formulations.
Preparation Method:
The preparation method of (R)-9-(2-hydroxypropyl) adenine is more complicated, and it is usually synthesized by organic synthesis reaction. Specific methods may vary according to different research needs.
Safety Information:
(R)-9-(2-Hydroxypropyl) adenine is a relatively safe chemical under normal operating conditions. However, because it is a chemical substance, it is still necessary to follow safe operating procedures when using and storing it. When exposed to (R)-9-(2-hydroxypropyl) adenine, care should be taken to avoid contact with eyes, skin, and respiratory tract, and protective gloves and goggles should be worn. At the same time, the safety operation regulations in the laboratory should be followed, and the safety data form or safety manual of the product should be read carefully before use. If you accidentally come into contact with (R)-9-(2-hydroxypropyl) adenine, rinse immediately with plenty of water and seek medical help if needed.
Last Update：2024-04-09 21:11:58
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